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May 22, 2023: Did you know that cutting-edge research highlights the link between symptoms very asthma and lung cancer?
About 25 million Americans have asthma, a chronic inflammatory airway disease that makes the the inner lining of the lungs swells. Between 5% and 10% of Americans with the disease have severe asthma. Severe asthma is classified according to the need for medium to high-dose corticosteroids and other long-acting medications. Often these medications will not control asthma symptoms, which people with asthma have every night and most days of the week.
The inflammation caused by asthma triggers attacks when patients inhale allergens such as pollen, dust, or pollutants.
Lung cancer is also driven by inflammation in the respiratory tract, which can contribute to the development of tumors.
“Inflammation appears to be related to malignancies,” said William L. Dahut, MD, chief scientific officer of the American Cancer Society. “Asthma inflammation may be one of the reasons people with asthma are more likely to get lung cancer.”
Severe asthma is also characterized by fibroblastscells that can promote inflammation. researchers they also link fibroblasts to lung cancer.
“In a basic laboratory studythe researchers found that invasive bronchial fibroblasts derived from asthmatic patients can activate lung cancer cells,” he said. Yi Guo, PhD, associate professor of health outcomes and biomedical informatics at the University of Florida College of Medicine in Gainesville. “Further studies are needed to explore this relationship in real-world patient populations.” (Guo is also a co-author of a new study which found that patients with asthma are almost one and a half times more likely to develop cancer than those with good respiratory health).
researchers in the United Arab Emirates have found that patients with severe asthma are often diagnosed with lung cancer after it has developed for 3 decades. This is important because it shows that the inflammation of severe asthma can contribute to long-term, low-level damage to lung tissue. Study authors working with Canadian researchers. further found that patients with severe asthma are more likely to be diagnosed with aggressive stage III or IV lung cancer, and that clinicians may want to consider severe asthma as a predictor of disease risk.
Read on to learn about the things that could put people with severe asthma at higher risk for lung cancer, as well as how to reduce those chances.
What are the symptoms of severe asthma?
He The symptoms of asthma are:
- cough
- Difficulty breathing
- wheezing
- Chest tightness
People with severe asthma may also breathe rapidly, have heart rate changes, and may strain the muscles in the head and neck from the stress of coughing or trying to get more air.
What are the symptoms of lung cancer?
There is two types of lung cancer. Adenocarcinoma occurs in up to 85% of patients and is also related to a subtype called squamous cell lung cancer. Small cell lung cancer, which occurs in only 15% of patients, grows and spreads faster. For patients with severe asthma, “the increased risk of lung cancer does not occur in adenocarcinoma, but is more common in small cell and squamous cell,” Dahut said.
Lung cancer symptoms include:
- A persistent or worsening cough
- Chest pain
- Difficulty breathing
- coughing up blood
- extreme fatigue
- unexplained weight loss
Some of the symptoms of lung cancer overlap with signs of severe asthma. It is important that people with severe asthma tell their doctor about any developments that concern them.
Should You Get Screened For Lung Cancer If You Have Severe Asthma?
At this time, the recommendations for the detection of lung cancer apply to patients who:
- Have a smoking history of 20 pack-years or more, and
- Smoking now, or quit smoking in the last 15 years, and
- You are between 50 and 80 years old
That said, risk can be very specific, so it’s important for people to do what’s right for them on an individual level.
“It’s important to follow your doctor’s recommendations,” he said. Alberto Rizzo, M.D., medical director of the American Lung Association. “If you have a family history of lung cancer, it’s also important to review it with your doctor.”
How can you reduce your risk of lung cancer if you have severe asthma?
To reduce the risk, it is important:
- Stay on top of your symptoms. Researchers in Norway recently discovered that patients with partially controlled lung cancer symptoms are at increased risk of lung cancer. If your asthma symptoms are well controlled, there is much less chance of damage to your lung tissue.
- Ask about how to adjust your medication.
“Some studies have also shown that patients who used inhaled glucocorticoids decrease the risk of lung cancer,” Dahut said. (Glucocorticoids not only fight inflammation in severe asthma, but also in cancer.) - Don’t smoke and avoid all secondhand smoke.
- Make your living space safer.
“Have your home inspected for radon gaswhich can increase your risk of lung cancer,” Rizzo said. - Avoid cancer-causing chemicals in the workplace. diesel fumes, for example, have been linked to an increased risk of lung cancer. Avoid exposing yourself to them while traveling and roll up your windows in traffic.
- Eat more fruits and vegetables. These foods contain powerful compounds which may have a protective effect. Broccoli, cauliflower, cabbage, bok choy, and Brussels sprouts contain sulforaphane, which may reduce the risk of cancer. Leafy green vegetables are packed with folic acid, which can also help prevent disease. Also, think orange: Foods that color, like oranges, tangerines, peaches, papayas, red bell peppers, and carrots, contain beta-cryptoxanthin, a cancer-fighting pigment.
- Get as much exercise as you can. Ask your doctor to recommend low-impact exercises that don’t cause shortness of breath.
“The more control you have over your lung cancer risk factors, the more your chances can go down,” Rizzo said. Bottom line: There are many things you can start doing today to live a longer, healthier life.
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