Occupational and environmental exhibitions can put specific groups of people with greater cancer risk, including firefighters. A new study by researchers from Mass Brigham general examines cancer rarely studied in firefighters: gliomas, a type of tumor that is formed in the brain or spinal cord. Using gliome tumors samples from the University of California, the Adult glioma study. The results are published in CANCERA magazine reviewed by pairs of the American Cancer Society.
“Identifying a mutation firm such as this is important because this can report public health intervention strategies,” said main author Elizabeth B. Claus, MD, PHD, from the Department of Neurosurgery of the Brigham Hospital and Women’s, founding member of the Brigham Mass General Health System. Claus also has an appointment at the Yale Public Health School. “Some occupational risks can be avoidable and identify them could help prevent gliomas.”
Claus and his colleagues compared genetic samples of tumors of 17 firefighters with tumors with 18 people who had never been firefighters. They found mutations linked to a known “mutational firm”, a unique pattern of genetic mutations, in many of the samples of firefighters, especially in those that had spent more years of fire fighting. Among the non -filtering, the highest signal of the firm was observed among the people who had possibly been exposed to Haloalkenos through other occupations, such as painting or being mechanical.
“In this pilot study, we confirm our previous findings of an association between exposure to the halockanes and the risk of glioma, we hope to examine this in larger samples that include both firefighters and other people exposed to Haloalkanes,” Claus said. “Our efforts to do so continue through the development of our online gliome record, an effort to study risk factors and treatments for glioma.”
Disseminations: Elizabeth B. Claus reports the rates of the Servier Pharmaceuticals Advisory Board outside the work presented. Additional disseminations of the author can be found in the document.